Dr John Mulley

Darlithydd Ymchwil

j.mulley@bangor.ac.uk

+44 1248 383492

Dr John Mulley

Evo-Devo@Bangor

My main research interest is in the way that genomic changes have influenced animal evolution and development. Current research projects focus on the GC-biased mutation in desert rodents, snake venom evolution, and the mechanisms by which the uterine environment can change gene expression in the embryo.

Location: Room E1, 4th floor Brambell Building

Telephone: +44 (0)1248 383492

Personal webpage:

Twitter: @

  • DPhil: The Evolution of Vertebrate ParaHox Genes
    Oxford University, 2007
  • MSc: Biosystematics
    Grand Challenges in Ecosystem and the Environment Initiative, Imperial College London, Silwood Park Campus, Ascot, Berkshire SL5 7PY, UK alexander.papadopulos@plants.ox.ac.uk., 2003
  • BSc: Genetics
    Department of Molecular and Clinical Pharmacology, University of Liverpool, 2002

Comparative genomics

I have a long-standing interest in vertebrate genome evolution, especially as it relates to gene and genome duplication, and/or the evolution of novelty. Whole genome duplications look likely to have played a significant role in the evolution of vertebrates, and particularly the development of vertebrate innovations, and gene duplication has been an important factor in the origin and diversification of snake venom.

Postgraduate opportunities in this area relate to the evolution of vertebrate homeobox genes; GC-biased mutation in desert rodents; and snake venom evolution, taking advantage of recent advances in long-read sequencing and techniques for the assembly of chromosome-scale genome assemblies such as Hi-C.

Evolution and Development (Evo-Devo)

Changes to embryonic development can have major effects on adult morphology, and the evolution of developmental processes has been a major driver of animal evolution.

Postgraduate opportunities in this area relate to my current research into vertebrate axial patterning, and particularly how the uterine environment might influence numbers and types of vertebrae in mouse models. These projects would require management of rodent breeding programs; collection of embryos; antibody-based hormones assays, and gene/protein expression studies. There is scope for expansion of this research into studies of human and non-human primate vertebral variation.  

Snake venom evolution

The availability of whole genome sequences for multiple snake species is providing unprecedented insight into the processes underlying the origin and diversification of snake venom. 91¾«Æ·ºÚÁÏ³Ô¹Ï is one of the few Universities in the UK that maintains a collection of venomous snakes, and this invaluable resource facilitates research into the genetic factors responsible for inter- and intra-species variation in snake venom composition.

Postgraduate opportunities in this area relate to the determination of the gene and genome level mechanisms that drive variation in venom composition within and between species.

2025

  • Cyhoeddwyd
    Major, T., Jeffrey, L., Limia Russel, G., Bracegirdle, R., Gandini, A., Morgan, R., Marshall, B., Mulley, J. & Wüster, W., 5 Chwef 2025, Yn: PLoS ONE. 20, 2, t. e0310352 22 t.
    Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
  • Cyhoeddwyd
    Owens, J. B., Wüster, W., Mulley, J., Graham, S., Morgan, R. & Barlow, A., 14 Ion 2025, Yn: Wellcome Open Research . 10, 11, 13 t.
    Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl

2024

  • Cyhoeddwyd
    Major, T., Jeffrey, L., Limia Russel, G., Bracegirdle, R., Gandini, A., Morgan, R., Marshall, B. M., Mulley, J. & Wüster, W., 3 Medi 2024, BioRxiv, 29 t.
    Allbwn ymchwil: Papur gweithio › Rhagargraffiad
  • Cyhoeddwyd
    Mayeur, H., Leyhr, J., Mulley, J., Leurs, N., Michel, L., Sharma, K., Lagadec, R., Aury, J.-M., Osborne, O. G., Mulhair, P., Poulain, J., Mangenot, S., Mead, D., Smith, M., Corton, C., Olive, K., Skelton, J., Betteridge, E., Dolucan, J. & Dudchenko, O. & 17 eraill, Omer, A. D., Weisz, D., Aiden, E. L., McCarthy, S., Sims, Y., Torrance, J., Tracey, A., Howe, K., Baril, T., Hayward, A., Martinand-Mari, C., Sanchez, S., Haitina, T., Martin, K., Korsching, S. I., Mazan, S. & Debiais-Thibaud, M., 6 Rhag 2024, Yn: Molecular Biology and Evolution. 41, 12
    Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid

2023

  • Cyhoeddwyd
    Brekke, T. D., Papadopulos, A. S. T., Julia, E., Fornas, O., Fu, B., Yang, F., de la Fuente, R., Page, J., Baril, T., Hayward, A. & Mulley, J., Mai 2023, Yn: Molecular Biology and Evolution. 40, 5, msad115.
    Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
  • Cyhoeddwyd
    Rogerson, G., Bock, S., Loera, Y., Parrott, B. & Mulley, J., 31 Maw 2023, Yn: Journal of Experimental Biology. 226, 6, jeb245219.
    Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
  • Cyhoeddwyd
    Major, T., Bracegirdle, R., Gandini, A., Limia Russel, G., Pozzi, A., Morgan, R., Mulley, J. & Wüster, W., 17 Ion 2023, Yn: Herpetology Notes. 16, t. 51-54 4 t.
    Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
  • Cyhoeddwyd
    Brekke, T. D., Shier, L., Hegarty, M. J. & Mulley, J., Medi 2023, Yn: Conservation Genetics Resources. 15, 3, t. 117-124 8 t.
    Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
  • Cyhoeddwyd
    Falk, S. & Mulley, J., 31 Ion 2023, Yn: Wellcome Open Research . 8, 43, t. 43
    Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
  • Cyhoeddwyd
    Mulley, J., Lees, D., programme, W. S. I. T. O. L. & Consortium, D. T. O. L., 20 Rhag 2023, Yn: Wellcome Open Research . 8, 578
    Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
  • Cyhoeddwyd
    Crowley, L. M., Telfer, M., Geiser, M. & Mulley, J., 13 Ebr 2023, Wellcome Open research, t. 169, (Wellcome open research).
    Allbwn ymchwil: Papur gweithio › Rhagargraffiad
  • Cyhoeddwyd
    Mulley, J. & Boyes, D., 9 Chwef 2023, Yn: Wellcome Open Research . 8, t. 66
    Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
  • Cyhoeddwyd
    Falk, S. & Mulley, J., 12 Ion 2023, Yn: Wellcome Open Research . 8, 17
    Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
  • Cyhoeddwyd
    Boyes, D., Mulley, J. F. & Consortium, D. T. O. L., 23 Maw 2023, Yn: Wellcome Open Research. 8, 129, t. 129 1 t.
    Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
  • Cyhoeddwyd
    Boyes, D. & Mulley, J., 8 Chwef 2023, Yn: Wellcome Open Research . 8, 63.
    Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
  • Cyhoeddwyd
    Falk, S. & Mulley, J., 8 Chwef 2023, Yn: Wellcome Open Research . 8, 65, t. 65
    Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
  • Cyhoeddwyd
    Boyes, D. & Mulley, J., 31 Ion 2023, Yn: Wellcome Open Research . 8, 45
    Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
  • Cyhoeddwyd
    Falk, S., Mulley, J. F. & Consortium, D. T. O. L., 30 Awst 2023, Yn: Wellcome Open Research. 8, 373
    Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
  • Cyhoeddwyd
    Boyes, D., Mulley, J., collective, D. T. O. L. B. & programme, W. S. I. T. O. L., 8 Medi 2023, Yn: Wellcome Open Research . 8, 399
    Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
  • Cyhoeddwyd
    Boyes, D., Mulley, J., collective, D. T. O. L. B. & programme, W. S. I. T. O. L., 12 Hyd 2023, Yn: Wellcome Open Research . 8, 441
    Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
  • Cyhoeddwyd
    Crowley, L. M., Mulley, J. F., Lab, U. O. O. A. W. W. G. A., collective, D. T. O. L. B., programme, W. S. I. T. O. L., collective, W. S. I. S. O. D. P., collective, T. O. L. C. I. & Consortium, D. T. O. L., 21 Meh 2023, Yn: Wellcome Open Research. 8, 258
    Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
  • Cyhoeddwyd
    Falk, S. & Mulley, J., 2 Meh 2023, Wellcome Open research, t. 234, (Wellcome open research).
    Allbwn ymchwil: Papur gweithio › Rhagargraffiad

2022

  • Cyhoeddwyd
    Mulley, J., Ebr 2022, Yn: Journal of Anatomy. 240, 4, t. 735-745 11 t.
    Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl adolygu › adolygiad gan gymheiriaid
  • Cyhoeddwyd
    Crowley, L. M. & Mulley, J., 5 Gorff 2022, Wellcome Open Research , 7, 178, t. 178 1 t.
    Allbwn ymchwil: Cyfraniad at gyhoeddiad arbenigol › Erthygl

2020

  • Cyhoeddwyd
    Payne, M., Mulley, J. & Winder, I. C., Ebr 2020.
    Allbwn ymchwil: Cyfraniad at gynhadledd › Crynodeb › adolygiad gan gymheiriaid
  • Cyhoeddwyd
    Parcana, R., Hargreaves, A. D., Mulley, J. & Holland, P. W. H., 1 Awst 2020, Yn: Molecular Biology and Evolution. 37, 8, t. 2197-2210 msaa072.
    Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid

2019

  • Cyhoeddwyd
    Brekke, T., Mulley, J., Steele, K., Denver, M., Thom, A. & Supriya, S., Ebr 2019, Yn: Mammalian Genome. 30, 3-4, t. 63-70 8 t.
    Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
  • Cyhoeddwyd
    Payne, M., Winder, I. C. & Mulley, J., 18 Rhag 2019.
    Allbwn ymchwil: Cyfraniad at gynhadledd › Murlen › adolygiad gan gymheiriaid
  • Cyhoeddwyd
    Mulley, J. F., Tach 2019, Yn: BioEssays : news and reviews in molecular, cellular and developmental biology. 41, 11
    Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
  • Cyhoeddwyd
    Zancolli, G., Calvete, J. J., Cardwell, M. D., Greene, H. W., Hayes, W. K., Hegarty, M. J., Herrmann, H.-W., Holycross, A. T., Lannutti, D. I., Mulley, J. F., Sanz, L., Travis, Z. D., Whorley, J. R., Wuster, C. E. & Wuster, W., 13 Maw 2019, Yn: Proceedings of the Royal Society B: Biological Sciences. 286, 1898, t. 20182735
    Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid

2018

  • Cyhoeddwyd
    Brekke, T., Steele, K. & Mulley, J., 1 Chwef 2018, Yn: G3: Genes, Genomes, Genetics. 8, 2, t. 679-686
    Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
  • Cyhoeddwyd
    Hawkins, P., McBride, A., Paiba, G., Rose, R., Prescott, M. J., Mulley, J., Izzard, S., Ridley, D., Kappel, S., Melotti, L. & Hubrecht, R., Hyd 2018, Yn: Animal Technology and Welfare. 17, 2, t. 75-42
    Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid

2017

  • Cyhoeddwyd
    Hargreaves, A. D., Zhou, L., Christensen, J., Marletaz, F., Liu, S., Li, F., Jansen, P. G., Spiga, E., Hansen, M. T., Pedersen, S. V. H., Biswas, S., Seriwaka, K., Fox, B. A., Taylor, W. R., Mulley, J., Zhang, G., Heller, R. S. & Holland, P. W. H., 18 Gorff 2017, Yn: Proceedings of the National Academy of Sciences of the United States of America: PNAS. 114, 29, t. 7677–7682
    Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid

2016

  • Cyhoeddwyd
    Braasch, I., Gehrke, A. R., Smith, J. J., Kawasaki, K., Manousaki, T., Pasquier, J., Amores, A., Desvignes, T., Batzel, P., Catchen, J., Berlin, A. M., Campbell, M. S., Barrell, D., Martin, K. J., Mulley, J. F., Ravi, V., Lee, A. P., Nakamura, T., Chalopin, D. & Fan, S. & 41 eraill, Wcisel, D., Cañestro, C., Sydes, J., Beaudry, F. E., Sun, Y., Hertel, J., Beam, M. J., Fasold, M., Ishiyama, M., Johnson, J., Kehr, S., Lara, M., Letaw, J. H., Litman, G. W., Litman, R. T., Mikami, M., Ota, T., Saha, N. R., Williams, L., Stadler, P. F., Wang, H., Taylor, J. S., Fontenot, Q., Ferrara, A., Searle, S. M., Aken, B., Yandell, M., Schneider, I., Yoder, J. A., Volff, J., Meyer, A., Amemiya, C. T., Venkatesh, B., Holland, P. W., Guiguen, Y., Bobe, J., Shubin, N. H., Di Palma, F., Alföldi, J., Lindblad-Toh, K. & Postlethwait, J. H., 7 Maw 2016, Yn: Nature Genetics.
    Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid

2015

  • Cyhoeddwyd
    Hargreaves, A. D., Tucker, A. S., Mulley, J. F., Gopalakrishnakone, P. (Golygydd) & Malhotra, M. (Golygydd), 8 Awst 2015, Evolution of Venomous Animals and Their Toxins: Toxicology. Springer Netherlands, t. 1-15
    Allbwn ymchwil: Pennod mewn Llyfr/Adroddiad/Trafodion Cynhadledd › Pennod
  • Cyhoeddwyd
    Hargreaves, A. D. & Mulley, J. F., 24 Tach 2015, Yn: PeerJ. t. e1441
    Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid

2014

  • Cyhoeddwyd
    Hargreaves, A. D. & Mulley, J. F., 27 Awst 2014, Yn: Toxicon. 90, t. 351-353
    Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
  • Cyhoeddwyd
    Mulley, J. F. & Holland, P. W., 1 Medi 2014, Yn: Journal of Experimental Zoology Part B: Molecular and Developmental Evolution. 322, 6, t. 352-358
    Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
  • Cyhoeddwyd
    Hargreaves, A. D., Swain, M. T., Hegarty, M. J., Logan, D. W. & Mulley, J. F., 30 Gorff 2014, Yn: Genome Biology and Evolution. 6, 8, t. 2088-2095
    Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
  • Cyhoeddwyd
    Hargreaves, A. D., Swain, M. T., Logan, D. W. & Mulley, J. F., 17 Hyd 2014, Yn: Toxicon. 92, t. 140-156
    Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
  • Cyhoeddwyd
    Mulley, J. F., Hargreaves, A. D., Hegarty, M. J., Heller, R. S. & Swain, M. T., 6 Rhag 2014, Yn: BMC Genomics. 15, 1074
    Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid

2010

  • Cyhoeddwyd
    Mulley, J. F. & Holland, P. W., 12 Mai 2010, Yn: Molecular Biology and Evolution. 27, 10, t. 2386-2391
    Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid

2009

  • Cyhoeddwyd
    Mulley, J. F., Zhong, Y. F. & Holland, P. W., 2 Medi 2009, Yn: BMC Evolutionary Biology. 9, t. 218
    Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid

2008

  • Cyhoeddwyd
    Furlong, R. F. & Mulley, J. F., 25 Hyd 2008, Yn: Zoological Science. 25, 10, t. 955-9 5 t.
    Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl adolygu › adolygiad gan gymheiriaid

2006

  • Cyhoeddwyd
    Mulley, J. F., Chiu, C.-H. & Holland, P. W. H., 5 Gorff 2006, Yn: Proceedings of the National Academy of Sciences of the United States of America. 103, 27, t. 10369-72 4 t.
    Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid

2004

  • Cyhoeddwyd
    Mulley, J. & Holland, P., 21 Hyd 2004, Yn: Nature. 431, 7011, t. 916-7 2 t.
    Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
  • Cyhoeddwyd
    Daly, D., Waltham, K., Mulley, J., Watts, P., Rosin, A., Kemp, S. & Saccheri, I., Meh 2004, Yn: Molecular Ecology Notes. 4, 2, t. 179-181
    Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid

2023

  • 25 Gorff 2023 – 27 Gorff 2023

    Gweithgaredd: Cymryd rhan mewn cynhadledd Academaidd (Trefnydd)

  • 01/06/2019 – 30/09/2023 (Wedi gorffen)

  • 01/02/2019 – 30/06/2020 (Wedi gorffen)

  • 01/11/2017 – 31/12/2017 (Wedi gorffen)

  • 01/11/2017 – 15/03/2018 (Wedi gorffen)

  • 01/02/2017 – 30/05/2018 (Wedi gorffen)

  • 01/06/2016 – 01/08/2019 (Wedi gorffen)

  • 01/04/2011 – 31/08/2012 (Wedi gorffen)

  • 01/02/2011 – 31/03/2013 (Wedi gorffen)

  • 01/08/2010 – 31/08/2014 (Wedi gorffen)